Palga Science Award

Voor wie is de award bedoeld?

De Palga Science Award staat open voor onderzoekers die gebruikmaken van de Palga-databank in hun wetenschappelijke werk. Dit kunnen zowel jonge onderzoekers als ervaren wetenschappers zijn, zolang hun onderzoek een substantiële bijdrage levert aan de pathologie en de bredere gezondheidszorg.

Selectieprocedure

Onderzoekers kunnen deelnemen door een abstract in te dienen waarin hun onderzoek wordt toegelicht. Een onafhankelijke jury, bestaande uit experts uit de pathologie en data-gedreven zorg, beoordeelt de inzendingen op basis van innovatie, wetenschappelijke kwaliteit en maatschappelijke impact.

Op basis van deze beoordeling worden drie genomineerden geselecteerd. Hun abstracts worden gepubliceerd op deze website en krijgen extra aandacht tijdens de voorjaarsdagen van de NVVP.

Uitreiking van de award

Tijdens de voorjaarsdagen van de NVVP presenteren de drie genomineerden hun onderzoek aan het publiek. De jury kiest vervolgens de winnaar, die de Palga Science Award in ontvangst mag nemen. Naast erkenning ontvangt de winnaar een geldbedrag als stimulans voor verder onderzoek.

Bekijk alle inzendingen in 2026 (willekeurige volgorde)

1. Occurrence of Malignancies Other than Breast and Ovarian Cancer in Female Carriers of a BRCA1/2 Germline Pathogenic Variant
2. The effect of bivalent HPV vaccination against invasive cervical cancer and cervical intraepithelial neoplasia grade 3 (CIN3+) in the Netherlands: a population-based linkage study
3. A Decade of C3 Glomerulopathy: a nationwide cohort study
4. Malignant extracranial germ cell tumors in the Netherlands between 1990 and 2018: Stable incidence and improved survival
5. HER2-LOW BREAST CANCER IN ROUTINE PRACTICE: A NATIONWIDE STUDY OF DIAGNOSTIC VARIABILITY ACROSS PATHOLOGY LABORATORIES
6. DECISION MAKING IN BREAST PATHOLOGY REPORTING: THE EFFECT OF CLINICAL RELEVANT THRESHOLDS
7. Frailty is not associated with alterations in the melanoma tumor microenvironment
8. AI-detected tumor-infiltrating lymphocytes and outcomes in anti-PD1 based treated melanoma
9. The Malignancy Risk of Thyroid Incidentalomas Detected by [18F]FDG PET/CT Lower than Expected: A Nationwide Observational Study in the Netherlands
10. Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma
11. Longitudinal data on advanced cutaneous squamous cell carcinoma from the Dutch Keratinocyte Cancer Collaborative (DKCC): a nationwide real-world database study
12. The SALV-Dataset Registry: an expertly curated digital clinicopathological dataset for salivary gland tumor research and AI-assisted diagnostic tools
13. Offer colonoscopy to patients with non-invasive appendiceal neoplasms
14. Gene expression profiling and current staging factors show comparable performance in predicting distant metastases in early-stage melanoma: results from the population-based Dutch Early-Stage Melanoma (D-ESMEL) study
15. Endoscopic Surveillance Detects Only a Minority of Barrett-Related Dysplasia and Cancer: evidence from a Nationwide Cohort
16. Distinguishing True Recurrence from Second Primary Breast Cancer by Molecular Clonality Analysis
17. Expert histopathological and molecular assessment for ambiguous primary cutaneous melanocytic tumours
18. A nationwide histopathology study reflecting the impact of the introduction of MRI in the diagnostic trajectory of prostate cancer in routine clinical care
19. Skin biopsies in neonatal and infantile erythroderma: a valuable diagnostic tool / A 30-year retrospective study in the Netherlands
20. Impact of COVID-19 on Oncological Outcomes During Follow-up in Gynaecological Cancer: A Nationwide Retrospective Cohort Study
21. Cervical cancer and pre-cancerous lesion risk prediction in hrHPV-positive women in screening
22. PD-L1 Testing in Triple-Negative Breast Cancer: National Practice and Interlaboratory Variation in the Netherlands
23. Immune infiltration in Lynch syndrome-associated colorectal cancer is linked to diagnostic context rather than the specific MMR gene defect
24. OTP, CD44, Ki-67 Immunohistochemistry to Predict Prognosis in Preoperative Lung Neuroendocrine Tumor Biopsy Specimens
25. Performance of primary self-sampling for HPV testing and genotyping in the new Dutch Cervical Cancer Screening Program
26. Subclassification of locoregional recurrent colon cancer based on location, treatment and survival
27. Incidence of Cervical Cancer in hrHPV-positive Patients with Low-grade Cytological Abnormalities: a Dutch Nationwide Cohort Study
28. Histopathological and spatially-informed molecular profiling of PMS2 Lynch syndrome-associated lesions
29. Long-term progression risk in Barrett’s esophagus: a nationwide cohort study
30. Histopathological evaluation of local effects of radioactive iodine seeds in axillary lymph nodes in clinically node-positive breast cancer treated with neoadjuvant systemic therapy
31. Diagnostic performance of cytological triage in cervical cancer screening among hrHPV-positive women with 7.5 years follow-up in the Netherlands
32. Prognostic value of the Combined Analysis of Pathology and Artificial Intelligence (CAPAI) in high-risk stage II-III colon cancer treated without chemotherapy: Interim report from a nationwide validation
33. Molecular subtypes of gastric adenocarcinoma and their relation to survival, response to chemotherapy and pattern of metastases – a post-hoc analysis in the prospective multicenter LOGICA-trial
34. Leveraging Multimodal Data for Risk Prediction in Ductal Carcinoma in Situ
35. A composite biomarker approach to withhold neoadjuvant chemotherapy in select muscle-invasive bladder cancer patients

Bekijk alle inzendingen in 2025 (willekeurige volgorde)

1. Diagnosis of patients with fibrolamellar carcinoma: a Dutch nationwide study
2. The impact of positive surgical margins after cystectomy on oncological outcomes: a nationwide study
3. Lower degree of microsatellite instability in colorectal carcinomas from MSH6-associated Lynch syndrome patients
4. Notification of locoregional breast cancer recurrence based on pathology reports: a nationwide validation study with the Netherlands Cancer Registry
5. Recurrent CLTC::SYK fusions and CSF1R mutations in juvenile xanthogranuloma of soft tissue
6. Placental lesions and key obstetric outcomes: a unique linked cohort study using PALGA national pathology and Perined pregnancy registries
7. The incidence of Castleman disease in The Netherlands: a retrospective study based on Dutch pathology reports
8. Nationwide Implementation and Evaluation of the Tumor-First Workflow for Genetic Testing in Ovarian Carcinoma
9. Leveraging Sequence-to-Sequence Models for Semantic Annotation of Dutch Pathology Reports
10. Artificial intelligence-based pRb subtyping of pulmonary large cell neuroendocrine carcinoma on small haematoxylin and eosin-stained specimens
11. OTP, CD44, and Ki-67: A prognostic marker panel for relapse free survival in patients with surgically resected pulmonary carcinoid
12. Identification of defined molecular subgroups based on immunohistochemical analyses and potential therapeutic vulnerabilities of pulmonary carcinoids
13. Combining PALGA and IKNL data to create a representative cohort for validating LY75 promoter methylation as a predictor of stage I–III melanoma patients at high risk of disease recurrence
14. Tumor-positive peritoneal cytology in patients with gastric cancer is associated with poor outcome: A nationwide study
15. Outcomes of endometrial cancer preven3on strategies in patients with Lynch syndrome: a nationwide cohort study in the Netherlands
16. Prevalence and Impact of Vulvar Lesions Diagnosed Prior to Vulvar Squamous Cell Carcinoma: A Population-Based Cohort Study
17. Using real-world data for machine-learning algorithms to predict the treatment response in advanced melanoma: a pilot study for personalizing cancer care
18. Outcomes of cervical cancer screening among women with HIV in the Netherlands
19. The prevalence and clinical relevance of cervical abnormalities after an amputation of the cervix as part of prolapse surgery: a cross-sectional study
20. The Dutch Early-Stage Melanoma Study (D-ESMEL): a Discovery Set and Validation Cohort to Predict the Absolute Risk of Distant Metastases in Stage I/II Cutaneous Melanoma
21. Incidence of cervical intraepithelial neoplasia and cervical cancer in transmasculine and gender diverse individuals using testosterone: a retrospective, single centre cohort study
22. A large language model based approach for extraction of molecular biomarker information from pathology reports: a nationwide study of EGFR and KRAS testing rates in patients with lung cancer in the Netherlands
23. Ductal Carcinoma In Situ of the breast: Potential to metastasize? A nationwide cancer registry-based study
24. Trends in liver resections over the past 30 years in The Netherlands
25. Prediction models are helpful for patients with a biopsy diagnosis of ductal carcinoma in situ
26. The effect of neoadjuvant chemotherapy on ductal carcinoma in situ in triple-negative breast cancer patients: a nationwide analysis
27. Early salpingectomy with delayed oophorectomy as alternative for risk-reducing salpingo-oophorectomy – the first 2000 participants in the ongoing international TUBA-WISP II study
28. Development and Validation of a Transcriptomic Classifier for Predicting Invasive Breast Cancer Risk in Ductal Carcinoma In Situ
29. Histopathologic Findings of Gynaecologic Tissue in Transmasculine and Gender Diverse individuals Using Testosterone: a Nationwide Cohort Study
30. Increased skin autofluorescence predicts future cancer development
31. High risk of colorectal cancer after high-grade dysplasia in inflammatory bowel disease patients
32. 10-year survival after resection of pancreatic ductal adenocarcinoma with pathological re-examination in a nationwide cohort
33. Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer
34. Expanding histopathological assessment provides limited prognostic value for metastatic cutaneous squamous cell carcinoma: insights from two nested case-control studies
35. Enabling Molecular Subtyping in DCIS: Leveraging Foundation Models for Robust Biomarker Scoring and Patient Stratification
36. Critical evaluation of sentinel lymph node biopsy in pT1b and pT2a melanoma: a nationwide population-based study
37. Deep Learning for Predicting Invasive Recurrence of Ductal Carcinoma In Situ of the breast: Leveraging Histopathology Images and Clinical Features
38. Loss to follow up after cervical intraepithelial neoplasia after referral to the general practitioner

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Meer informatie & deelname

Wil je meer weten over de Palga Science Award of zelf deelnemen? Houd deze pagina in de gaten voor de volgende ronde van inschrijvingen of neem contact met ons op via stichting@palga.nl.